I know you havent had any adverse effects and it works for you, but that is most likely because you are young and your liver is still youthful and healthy.

The problem with tylenol and excedrin is that the active ingredient is acetaminophen, which is metabolized by the liver. Alcohol is also metabolized by the liver. This is too much for the liver to store, filtrate, and remove effectively. Alcohol is metabolized first, which can leave extra toxic acetaminophen toxins. This condition is called hepatotoxicity and can lead to acute liver failure.

In summary, taking acetaminophen after drinking overwhelms the liver’s ability to effectively remove toxins from your blood stream.

Also, it takes about 5 days for alcohol to be completely metabolized and removed from the liver. Acetaminophen takes longer. So basically, for people that drink more than once a week, you shouldnt take acetaminophen.

Advil is a little safer, however if you take too much ibuprophen mixed with alcohol it can lead to gastrointestinal bleeding.

So in reality you should avoid pain relievers and alcohol all together. I just like to let my liver detox the alcohol alone without any other competition

Haha. I love this ’cause I thought this was going to be kind of a message with TIPS on how to avoid hangovers. I guess I was wrong. )

In my case, I haven’t FELT hung-over. ‘Cause ever since I was in fourth grade, I’ve had these twice-a-year-migraines. And boy, do they hurt. I actually cry when I have one of these. An I hug the toilet too. Maybe the headaches are the things that made my system kinda resistant to hangovers. Just sharing. )

Good luck to all the groggy people out there. >:D